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VNN1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989744
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50-198-9744 100 μL
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Catalog No. 50-198-9744 Supplier Bioss Supplier No. BS10314R
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Rabbit Polyclonal Antibody

Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes. GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells. Vanin-1 is ubiquitously expressed as a pantetheinase enzyme and catalyzes the hydrolysis of pantetheine for vitamin B5 recycling. The hydrolytic activity of vanin-1 generates the potent antioxidant cysteamine as a metabolite. As a membrane bound pantetheinase, vanin-1 provides the main source of cysteamine under normal physiological conditions. In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, where it aids in cell migration.

Specifications

Antigen VNN1
Applications Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH
Gene VNN1
Gene Accession No. O95497
Gene Alias HDLCQ8; Pantetheinase; Pantetheine hydrolase; Tiff66; V-1; vanin 1; Vanin1; Vanin-1; vannin 1; Vascular non-inflammatory molecule 1; VNN1
Gene Symbols VNN1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human VNN1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8876
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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