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Von Willebrand Factor Antibody (SPM577), Novus Biologicals™
SDP

Catalog No. p-7105490 Shop All R&D Systems Products
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0.02 mg
0.1 mg
0.2 mg
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Catalog No. Quantity
NBP233004F 0.02 mg
NBP233004A 0.1 mg
NBP233004B 0.2 mg
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Catalog No. NBP233004F Supplier Novus Biologicals Supplier No. NBP2330040.02MG
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Description

Mouse Monoclonal Antibody

Von Willebrand Factor Monoclonal specifically detects Von Willebrand Factor in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen Von Willebrand Factor
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SPM577
Conjugate Unconjugated
Dilution Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P04275
Gene Alias coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF
Gene Symbols VWF
Host Species Mouse
Immunogen Recombinant human vWF fragment
Molecular Weight of Antigen 250 kDa
Purification Method Protein A purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Cancer
Primary or Secondary Primary
Gene ID (Entrez) 7450
Test Specificity Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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