von Willebrand Factor, Rabbit anti-Human, Mouse, Rat, Polyclonal, Millipore Sigma™

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma AB735625UG

Catalog No. AB735625UG

Description

This Anti-von Willebrand Factor Antibody is validated for use in ELISA, Immunohistochemistry (IHC) for the detection of von Willebrand Factor.

von Willebrand Factor (vWF) is synthesized by endothelial cells, causing adhesion of platelets to injured vessel walls and functions as a carrier and stabilizer for coagulation of Factor VIII. It is one of the most widely used endothelial cell markers for studying angiogenesis / neovascularization. Millipore's von Willebrand Factor antibody reacts specifically with the endothelial cells of blood vessels and is a useful marker for the identification of endothelial lineage in tumors.

Specifications

• Antigen: von Willebrand Factor
• Classification: Polyclonal
• Dilution: ELISA: A 1:1000-1:5000 dilution of a previous lot was used in direct ELISA.Optimal working dilutions must be determined by the end user.
• Gene Alias: Factor VIII Related Antigen
• Host Species: Rabbit
• Molecular Weight of Antigen: 250 kDa
• Quantity: 25 μg
• Research Discipline: Cell Structure
• Gene ID (Entrez): NM_000552.3
• Target Species: Human, Mouse, Rat
• Form: Purified

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Formulation: Purified rabbit immunoglobulin in buffer containing 0.02 M PBS pH 7.6, 0.25 M NaCl with 0.1% sodium azide.
• Gene Symbols: VWF;F8VWF;F8;vWF;VWD
• Immunogen: Human von Willebrand Factor purified from plasma.
• Purification Method: Protein A Purfied
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: AB7356 is specific for vWF by ELISA against the human protein and by immunohistochemistry. The antibody is reactive in paraffin embedded tissues on human, rat, and mouse. Other species not tested. Antibody has not been evaluated by western blot analysis for reactivity to vWF.
• Content And Storage: Stable for 1 year at 2-8ºC from date of receipt.