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Invitrogen™ Human Parvovirus VP2 Monoclonal Antibody (4E5A4)
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Catalog No. PIMA538659
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100 μg
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PIMA538659 100 μg
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Catalog No. PIMA538659 Supplier Invitrogen™ Supplier No. MA538659
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Description

Mouse Monoclonal Antibody

This antibody has been tested in indirect ELISA.

Isoform VP2 is a structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers. Participates in host cell receptor binding together with VP1. Following virus endocytosis and trafficking to the endoplasmic reticulum, VP2 and VP3 form oligomers and integrate into the endoplasmic reticulum membrane. Heterooligomer VP2-VP3 may create a viroporin for transporting the viral genome across the endoplasmic reticulum membrane to the cytoplasm. Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2 or Vp3 nuclear localization signal (shared C-terminus). Plays a role in virion assembly within the nucleus in particular through a DNA-binding domain located in the C-terminal region. A N-terminal myristoylation suggests a scaffold function for virion assembly.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Human Parvovirus VP2
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4E5A4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Host Species Mouse
Immunogen Purified recombinant fragment of parovirus VP2 (aa: 296-438) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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