Invitrogen™ VPS16 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590792

Catalog No. PIPA590792

Description

Immunogen sequence: EYEPRSGEQV PLLLKMKRSK LALSKAIESG DTDLVFTVLL HLKNELNRGD FFMTLRNQPM ALSLYRQFCK HQELETLKDL YNQDDNHQEL GSFHIRASYA AEERIEGRVA ALQTAADAFY KAKNEFAAKA TEDQMRLLRL QRRLEDELGG QFLDLSLHDT VTTLILGGHN KRAEQLARDF RIPDKRLWWL KLTALADLED WEELEKFSKS KKSPIGYLPF VEICMKQHNK YEAKKYASRV GPEQKVKALL LVGDVAQAAD VAIEHRNEAE LSLVLSHCTG ATDGATADKI QRARAQAQKK; Positive Samples: A-549, Mouse brain, Mouse lung, Rat pancreas; Cellular Location: Cytoplasmic side, Cytoplasmic vesicle, Early endosome, Late endosome membrane, Lysosome membrane, Peripheral membrane protein, autophagosome, clathrin-coated vesicle.

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009].

Specifications

• Antigen: VPS16
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VPS16
• Gene Alias: 1810074M16Rik; hVPS16; mVPS16; RP11-12M19.2; vacuolar protein sorting 16 (yeast); vacuolar protein sorting 16 homolog; vacuolar protein sorting 16 homolog (S. cerevisiae); vacuolar protein sorting protein 16; vacuolar protein sorting-associated protein 16 homolog; VPS16; VPS16 CORVET/HOPS core subunit; VPS16, CORVET/HOPS core subunit
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 296159, 64601, 80743
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.52 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q920Q4, Q9H269
• Gene Symbols: VPS16
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 540-839 of human VPS16 (NP_0720972).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG