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Invitrogen™ VPS33B Polyclonal Antibody
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Catalog No. PIPA597158
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PIPA597158 100 μL
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Catalog No. PIPA597158 Supplier Invitrogen™ Supplier No. PA597158
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Rabbit Polyclonal Antibody

Immunogen sequence: CESIMKKKTK QDFQELIKTE HALLEGFNIR ESTSYIEEHI DRQVSPIESL RLMCLLSITE NGLIPKDYRS LKTQYLQSYG PEHLLTFSNL RRAGLLTEQA PGDTLTAVES KVSKLVTDKA AGKITDAFSS LAKRSNFRAI SKKLNLIPRV DGEYDLKVPR DMAYVFGGAY VPLSCRIIEQ VLERRSWQGL DEVVRLLNCS DFAFTDMTKE DKASSESLRL ILVVFLGGCT FSEISALRFL GREKGYRFIF LTTAVTNSAR LMEAMSEVKA; Positive Samples: A-549, MCF7, DU145; Cellular Location: Cytoplasmic side, Cytoplasmic vesicle, Early endosome, Late endosome membrane, Lysosome membrane, Peripheral membrane protein, Recycling endosome, clathrin-coated vesicle.

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VPS33B
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene VPS33B
Gene Accession No. P59016, Q9H267
Gene Alias FLJ14848; hVPS33B; r-vps33b; vacuolar protein sorting 33 homolog B; vacuolar protein sorting 33 homolog B (yeast); vacuolar protein sorting 33B; vacuolar protein sorting 33B (yeast); vacuolar protein sorting 33-like protein B; vacuolar protein sorting homolog r-vps33b; vacuolar protein sorting-associated protein 33B; vacuolar sorting protein 33b; vps33b; VPS33B late endosome and lysosome associated; VPS33B, late endosome and lysosome associated; zgc:110803
Gene Symbols VPS33B
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 348-617 of human VPS33B (NP_0611383).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 233405, 26276
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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