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Invitrogen™ VPS34 Recombinant Rabbit Monoclonal Antibody (9U5O3)
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Catalog No. PIMA535160
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100 μL
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PIMA535160 100 μL
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Catalog No. PIMA535160 Supplier Invitrogen™ Supplier No. MA535160
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: GGTQSEQYQE FRKQCYTAFL HLRRYSNLIL NLFSLMVDAN IPDIALEPDK TVKKVQDKFR LDLSDEEAVH YMQSLIDESV HALFAAVVEQ IHKFAQYWRK.

PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. PIK3C3 phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes. PIK3C3 is involved in coupling nutrient signaling to mTOR and also plays a role in autophagy and intracellular trafficking. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VPS34
Applications ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 9U5O3
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Pik3c3
Gene Accession No. O88763, Q6PF93
Gene Alias 5330434F23Rik; catalytic phosphatidylinositol 3-kinase 3; catalytic subunit type 3 Antibody; class 3 phosphoinositide-3-kinase; Class III PI 3-kinase; hVps34; hVps34 Antibody; OTTMUSP00000023341; OTTMUSP00000023350; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-kinase catalytic subunit type 3; phosphatidylinositol 3-kinase p100 subunit; phosphatidylinositol 3-kinase, catalytic subunit type 3; Phosphoinositide-3-kinase class 3; phosphoinositide-3-kinase, class 3; PI3K type 3; PI-3K Vps34p; pi3kc3; PI3-kinase type 3; Pik3c3; PIK3C3 Antibody; PtdIns-3-kinase type 3; VPS34
Gene Symbols Pik3c3
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 788-887 of human PIK3C3/VPS34 (Q8NEB9).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 225326, 65052
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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