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Invitrogen™ VPS37A Polyclonal Antibody
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Catalog No. PIPA589650
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100 μL
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PIPA589650 100 μL
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Catalog No. PIPA589650 Supplier Invitrogen™ Supplier No. PA589650
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MPDVPDAFPE LSELSVSQLT DMNEQEEVLL EQFLTLPQLK QIITDKDDLV KSIEELARKN LLLEPSLEAK RQTVLDKYEL LTQMKSTFEK KMQRQHELSE SCSASALQAR LKVAAHEAEE ESDNIAEDFL EGKMEIDDFL SSFMEKRTIC HCRRAKEEKL QQAIAMHSQF HAPL; Positive Samples: MCF7, HepG2, Mouse liver; Cellular Location: Late endosome membrane, Nucleus, Peripheral membrane protein.

This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VPS37A
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.81 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Vps37a
Gene Accession No. Q8CHS8, Q8NEZ2
Gene Alias 2210018P21Rik; 4930592A21Rik; AW261445; D8Ertd531e; ESCRT-I complex subunit VPS37A; HCRP1; Hepatocellular carcinoma-related protein 1; hVps37A; polyglutamine binding protein 2; PQBP2; SPG53; vacuolar protein sorting 37 homolog A; vacuolar protein sorting 37 homolog A (S. cerevisiae); vacuolar protein sorting 37A; vacuolar protein sorting 37A (yeast); vacuolar protein sorting-associated protein 37A; Vps37A; VPS37A, ESCRT-I subunit
Gene Symbols Vps37a
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 224-397 of human VPS37A (NP_6896282).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 137492, 290775, 52348
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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