Invitrogen™ VPS4A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577129

Catalog No. PIPA577129

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18.

Specifications

• Antigen: VPS4A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VPS4A
• Gene Alias: 4930589C15Rik; AI325971; AW553189; hVPS4; Protein SKD2; SKD1; SKD1A; SKD1-homolog; SKD2; vacuolar protein sorting 4 homolog A; vacuolar protein sorting 4 homolog A (S. cerevisiae); vacuolar protein sorting 4a; vacuolar protein sorting 4a (yeast); vacuolar protein sorting factor 4A; vacuolar protein sorting protein 4a; vacuolar protein sorting-associated protein 4A; vacuolar sorting protein 4; VPS4; VPS4-1; VPS4A; vps4-A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27183
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UN37
• Gene Symbols: VPS4A
• Immunogen: Recombinant full length Human VPS4A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG