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Invitrogen™ VPS4B Polyclonal Antibody
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Catalog No. PIPA590678
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100 μL
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PIPA590678 100 μL
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Catalog No. PIPA590678 Supplier Invitrogen™ Supplier No. PA590678
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSSTSPNLQK AIDLASKAAQ EDKAGNYEEA LQLYQHAVQY FLHVVKYEAQ GDKAKQSIRA KCTEYLDRAE KLKEYLKNKE KKAQKPVKEG QPSPADEKGN DSDGEGESDD PEKKKLQNQL QGAIVIERPN; Positive Samples: Mouse kidney, Mouse heart; Cellular Location: Late endosome membrane, Peripheral membrane protein, Prevacuolar compartment membrane.

The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VPS4B
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.72 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene VPS4B
Gene Accession No. P46467
Gene Alias 8030489C12Rik; cell migration-inducing 1; cell migration-inducing gene 1 protein; MIG1; Protein SKD1; SKD1; SKD1B; Suppressor of K(+) transport growth defect 1; suppressor of K+ transport defect 1; vacuolar protein sorting 4 homolog B; vacuolar protein sorting 4 homolog B (S. cerevisiae); vacuolar protein sorting 4B; vacuolar protein sorting 4b (yeast); vacuolar protein sorting-associated protein 4B; VPS42; VPS4-2; Vps4b
Gene Symbols VPS4B
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human VPS4B (NP_0048602).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20479
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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