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Invitrogen™ VPS4B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530316

Catalog No. PIPA530316


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Description

Description

Recommended positive controls: 293T. Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (88%), Xenopus laevis (88%), Chicken (89%), Rhesus Monkey (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

VPS4B
Polyclonal
Unconjugated
VPS4B
8030489C12Rik; cell migration-inducing 1; cell migration-inducing gene 1 protein; MIG1; Protein SKD1; SKD1; SKD1B; Suppressor of K(+) transport growth defect 1; suppressor of K+ transport defect 1; vacuolar protein sorting 4 homolog B; vacuolar protein sorting 4 homolog B (S. cerevisiae); vacuolar protein sorting 4B; vacuolar protein sorting 4b (yeast); vacuolar protein sorting-associated protein 4B; VPS42; VPS4-2; Vps4b
Rabbit
Antigen Affinity Chromatography
RUO
9525
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1.27 mg/mL
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
O75351
VPS4B
Recombinant fragment corresponding to a region within amino acids 176 and 433 of Human VPS4B.
100 μL
Primary
Human
Antibody
IgG
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