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Invitrogen™ VPS72 Polyclonal Antibody
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Catalog No. PIPA527626
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100 μL
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PIPA527626 100 μL
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Catalog No. PIPA527626 Supplier Invitrogen™ Supplier No. PA527626
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Molt-4. Predicted reactivity: Mouse (98%), Rat (98%), Rabbit (99%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Vacuolar protein sorting-associated protein 72 homolog (VPS72), also known as VPS72 or Transcription factor-like 1, is a 364 amino acid subunit of the TRRAP/TIP60 HAT complex. VPS72 has also been identified as a subunit of a novel complex containing SNF2-related helicase SRCAP (SWI2/SNF2-related CBP activator protein). This SRCAP-containing complex is very similar to the S. cerevisiae SWR1 chromatin remodeling complex. The involvement of VPS72 in these complexes has suggested that VPS72 plays multiple roles in chromatin modification and remodeling in cells. VPS72 localizes to the nucleus and is phosphorylated upon DNA damage, most likely by ATM or ATR.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VPS72
Applications Western Blot
Classification Polyclonal
Concentration 0.32 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene VPS72
Gene Accession No. Q15906
Gene Alias CFL1; Protein YL-1; Swc2; T YL-1; TCFL1; Transcription factor-like 1; transformation suppressor gene YL-1; vacuolar protein sorting 72 (yeast); vacuolar protein sorting 72 homolog; vacuolar protein sorting 72 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 72 homolog; VPS72; Yl1; YL-1
Gene Symbols VPS72
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human VPS72. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6944
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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