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Invitrogen™ VPS72 Polyclonal Antibody
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Catalog No. PIPA566792
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100 μL
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PIPA566792 100 μL
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Catalog No. PIPA566792 Supplier Invitrogen™ Supplier No. PA566792
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RKTAGNRLSGL LEAEEEDEFY QTTYGGFTEE SGDDEYQGDQ SDTEDEVDSD FDIDEGDEPS SDGEAEE Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.

Vacuolar protein sorting-associated protein 72 homolog (VPS72), also known as VPS72 or Transcription factor-like 1, is a 364 amino acid subunit of the TRRAP/TIP60 HAT complex. VPS72 has also been identified as a subunit of a novel complex containing SNF2-related helicase SRCAP (SWI2/SNF2-related CBP activator protein). This SRCAP-containing complex is very similar to the S. cerevisiae SWR1 chromatin remodeling complex. The involvement of VPS72 in these complexes has suggested that VPS72 plays multiple roles in chromatin modification and remodeling in cells. VPS72 localizes to the nucleus and is phosphorylated upon DNA damage, most likely by ATM or ATR.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VPS72
Applications ChIP Assay, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene VPS72
Gene Accession No. Q15906
Gene Alias CFL1; Protein YL-1; Swc2; T YL-1; TCFL1; Transcription factor-like 1; transformation suppressor gene YL-1; vacuolar protein sorting 72 (yeast); vacuolar protein sorting 72 homolog; vacuolar protein sorting 72 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 72 homolog; VPS72; Yl1; YL-1
Gene Symbols VPS72
Host Species Rabbit
Immunogen Recombinant Human VPS72. Recombinant protein control fragment (Product #RP-107449).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6944
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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