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Invitrogen™ VPS8 Monoclonal Antibody (2C8)
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Catalog No. PIMA524456
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100 μg
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Catalog No. Quantity
PIMA524456 100 μg
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Catalog No. PIMA524456 Supplier Invitrogen™ Supplier No. MA524456
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Description

Mouse Monoclonal Antibody

Peptide Sequence: RITPSQVKMS PSYHQSKGDP TAKKGTSEPV LDPQQIQAFD QLCRLYRGSS RLALLTELSQ NRSSESYRPF SGSQSAPAFN SIFQNENFQL QLIPPPVTED.

Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290). Functions predominantly in APPL1-containing endosomes (PubMed:25266290). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen VPS8
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 2C8
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene VPS8
Gene Accession No. Q8N3P4
Gene Alias AI315068; AU040738; im:7166005; KIAA0804; mKIAA0804; RGD1309443; si:dkey-24b15.1; vacuolar protein sorting 8 homolog; vacuolar protein sorting 8 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 8 homolog; VPS8; VPS8 CORVET complex subunit; VPS8 subunit of CORVET complex; VPS8, CORVET complex subunit; zgc:158695
Gene Symbols VPS8
Host Species Mouse
Immunogen KIAA0804 (NP_001009921, 1329 a.a. ~ 1428 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23355
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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