Invitrogen™ VSX1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597243

Catalog No. PIPA597243

Description

Immunogen sequence: MTGRDSLSDG RTSSRALVPG GSPRGSRPRG FAITDLLGLE AELPAPAGPG QGSGCEGPAV APCPGPGLDG SSLARGALPL GLGLLCGFGT QPPAAARAPC LLLADVPFLP PRGPEPAAPL APSRPPPALG RQKRSDSVST SDEDSQSEDR NDLKASPTLG KRKKRRHRTV; Positive Samples: A-549; Cellular Location: Nucleus.

VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in VSX1 can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: VSX1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VSX1
• Gene Alias: CAASDS; CHX10-like; homeodomain protein RINX; KTCN; KTCN1; PPCD; PPCD1; PPD; Retinal inner nuclear layer homeobox protein; RINX; Transcription factor VSX1; visual system homeobox 1; visual system homeobox 1 homolog (zebrafish); VSX1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 30813
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.55 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9NZR4
• Gene Symbols: VSX1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human VSX1 (NP_0554032).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG