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Tocris Bioscience™ VTP 27999 trifluoroacetate
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Catalog No. 556310
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10 mg
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Catalog No. Quantity
55-631-0 10 mg
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Catalog No. 55-631-0 Supplier Tocris Bioscience™ Supplier No. 5563/10
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Description

Highly potent and selective renin inhibitor

VTP 27999 trifluoroacetate is a highly potent and selective renin inhibitor (IC50 = 0.47 nM). Displays >1000-fold selectivity over related and unrelated off-targets. Blocks renin-stimulated ERK1/2 phosphorylation in vascular smooth muscle cells. Exhibits a different mode of action to aliskiren (Cat. No. 5491).

Specifications

Chemical Name or Material Methyl N-[2-[(R)-(3-Chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]carbamate trifluoroacetate
CAS 1013937-63-7
Quantity 10 mg
Target Additional Synthetic Protease Inhibitors
Molecular Formula C26H41ClN4O5.CF3CO2H
Formula Weight 639.1
Purity >97%
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