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  5. Tocris Bioscience™ VU 0134992

Tocris Bioscience™ VU 0134992
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Catalog No. 687750
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Catalog No. Quantity
68-775-0 50 mg
68-771-0 10 mg
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Catalog No. 68-775-0 Supplier Tocris Bioscience™ Supplier No. 6877/50
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Description

Kir4.1 blocker

VU 0134992 is a Kir4.1 potassium channel blocker (IC50 = 0.97 μM). Displays 10-fold selectivity for Kir4.1 over Kir4.1/5.1 concatemeric channels and >30-fold selectivity over Kir1.1, 2.1 and 2.2. Increases urine output and urinary Na+ and K+ excretion in volume-loaded rats.

Specifications

Quantity 50 mg
Molecular Formula C20H31BrN2O2
Formula Weight 411.38
Product Type Blocker
Purity 98%
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