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Tocris Bioscience™ VU 0409551

Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable

Manufacturer:  Tocris Bioscience™ 5693/50

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Catalog No. 56-935-0


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Description

Description

Selective mGlu5 positive allosteric modulator (EC50 = 260 nM). Selective for mGlu5 over other mGluR subtypes, as well as 66 other receptors and ion channels. Selectively potentiates mGlu5 signaling via Gαq. Exhibits wake-promoting, antipsychotic-like and cognition-enhancing effects in animal models. Brain penetrant and orally available.
Specifications

Specifications

[6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone
C20H17FN2O3
JNJ 46778212
Target: Group I mGluR Modulators
1363281-27-9
352.36
50mg
>98%
Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

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