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Tocris™ VU 6001966

Potent and selective negative allosteric modulator of mGlu2 receptors

Supplier:  Tocris™ 6928/5

Catalog No. 69-285


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Description

Description

VU 6001966 is a potent and selective mGlu2 negative allosteric modulator (IC50 = 78 nM). Exhibits > 350-fold selectivity for mGlu2 over mGlu3. Also exhibits selectivity over other mGluRs and a panel of GPCRs, ion channels and transporters. VU 6001966 induces antidepression like effects in mouse models of chronic stress. CNS penetrant.
Specifications

Specifications

2009052-76-8
Group II mGluR Modulators
2424
5 mg
C17H15FN4O2
98%
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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