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Tocris Bioscience™ VU 6001966
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Catalog No. 69285
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69-285 5 mg
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Catalog No. 69-285 Supplier Tocris Bioscience™ Supplier No. 6928/5
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Description

Potent and selective negative allosteric modulator of mGlu2 receptors

VU 6001966 is a potent and selective mGlu2 negative allosteric modulator (IC50 = 78 nM). Exhibits > 350-fold selectivity for mGlu2 over mGlu3. Also exhibits selectivity over other mGluRs and a panel of GPCRs, ion channels and transporters. VU 6001966 induces antidepression like effects in mouse models of chronic stress. CNS penetrant.

Specifications

CAS 2009052-76-8
Quantity 5 mg
Target Group II mGluR Modulators
Molecular Formula C17H15FN4O2
Formula Weight 2424
Purity 98%
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