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Tocris Bioscience™ VX 765

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Quantity:
10 mg
50 mg
Description
VX 765 is a high affinity and selective caspase-4 and caspase 1/ICE inhibitor (Ki of <0.6 and 0.8 nM, respectively). Prodrug of VRT-043198. Inhibits LPS-induced IL-1β production ∼ 60% in collagen-induced arthritis mouse model. Exhibits anticonvulsant effects in mouse model of acute seizures. Anti-inflammatory. Orally bioavailable.
Specifications
Specifications
Chemical Name or Material | N-(4-Amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(2 R,3 S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-L-prolinamide |
CAS | 273404-37-8 |
Quantity | 50 mg |
Target | Caspase Inhibitors |
Molecular Formula | C24H33ClN4O6 |
Purity | 0.98 |
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