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  5. Tocris Bioscience™ W 54011

Tocris Bioscience™ W 54011
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Catalog No. 545510
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Description

High affinity C5a receptor antagonist

W 54011 is a high affinity C5a receptor antagonist (Ki = 2.2 nM). Inhibits C5a-induced generation of reactive superoxide species, chemotaxis and intracellular Ca2+ mobilization in human neutrophils (IC50 values are 1.6, 2.7 and 3.1 nM, respectively).

Specifications

Chemical Name or Material N-[[4-(Dimethylamino)phenyl]methyl]-1,2,3,4-tetrahydro-7-methoxy-N-[4-(1-methylethyl)phenyl]-1-naphthalenecarboxamide hydrochloride
CAS 405098-33-1
Quantity 10 mg
Target Complement Signaling inhibitors
Molecular Formula C30H36N2O2.HCl
Formula Weight 493.08
Purity >98%
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