Invitrogen™ WBP1L Monoclonal Antibody (OPAL1-01)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA528627

Catalog No. PIMA528627

Description

This antibody recognizes an intracellular epitope of OPAL1 (outcome predictor in acute leukemia 1), a transmembrane adaptor protein expressed mainly by megakaryocytes and platelets. Western Blot: non-reducing conditions recommended.

WBP1L (OPAL1, outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megakaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.

Specifications

• Antigen: WBP1L
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 15mM sodium azide; pH 8
• Gene Accession No.: Q9NX94
• Gene Symbols: WBP1L
• Immunogen: Recombinant fragment of human OPAL1 (amino acids 152-342).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Western Blot
• Clone: OPAL1-01
• Conjugate: Unconjugated
• Gene: WBP1L
• Gene Alias: C10orf26; OPA1L; OPAL1; Outcome predictor in acute leukemia 1; WBP1L; WW domain binding protein 1-like
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 54838
• Content And Storage: 4°C, do not freeze
• Form: Liquid