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Invitrogen™ WDR24 Polyclonal Antibody
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Catalog No. PIPA578598
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100 μL
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PIPA578598 100 μL
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Catalog No. PIPA578598 Supplier Invitrogen™ Supplier No. PA578598
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Description

Rabbit Polyclonal Antibody

Positive Control: MCF-7, U87-MG Predicted Reactivity: Mouse (100%), Rat (100%), Zebrafish (87%), Xenopus laevis (90%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

WDR24, as a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. WDR24 is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1. In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WDR24
Applications Western Blot
Classification Polyclonal
Concentration 4.38 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.025% ProClin 300; pH 7
Gene WDR24
Gene Accession No. Q96S15
Gene Alias BC037651; C16orf21; GATOR complex protein WDR24; JFP7; WD repeat domain 24; WD repeat-containing protein 24; Wdr24
Gene Symbols WDR24
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human WDR24. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84219
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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