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Invitrogen™ WDR39 Polyclonal Antibody
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Catalog No. PIPA596650
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100 μL
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PIPA596650 100 μL
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Catalog No. PIPA596650 Supplier Invitrogen™ Supplier No. PA596650
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MKDSLVLLGR VPAHPDSRCW FLAWNPAGTL LASCGGDRRI RIWGTEGDSW ICKSVLSEGH QRTVRKVAWS PCGNYLASAS FDATTCIWKK NQDDFECVTT LEGHENEVKS VAWAPSGNLL ATCSRDKSVW VWEVDEEDEY ECVSVLNSHT QDVKHVVWHP SQELLASASY DDTVKLYREE EDDWVCCATL EGHESTVWSL AFDPSGQRLA SCSDDRTVRI WRQYLPGNEQ GVACSGSDPS WKCICTLSGF HSRTIYDIAW CQLTGALATA CGDDAIRVFQ EDPNSDPQQP TFSLTAHLHQ AHSQDVNCVA WNPKEPGLLA SCSDDGEVAF WKYQRPEGL; Positive Samples: Jurkat, Mouse kidney, Mouse thymus, Mouse heart, Rat heart.

WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WDR39
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.68 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CIAO1
Gene Accession No. O76071, Q5M7T1, Q99KN2
Gene Alias AW210570; CIA1; ciao1; ciao1 {ECO:0000255; cytosolic iron-sulfur assembly component 1; cytosolic iron-sulfur protein assembly 1; cytosolic iron-sulfur protein assembly 1 homolog; HAMAP-Rule:MF_03037}; probable cytosolic iron-sulfur protein assembly protein CIAO1; probable cytosolic iron-sulfur protein assembly protein CIAO1 {ECO:0000255; WD repeat domain 39; WD repeat-containing protein 39; WD repeat-containing protein 39 {ECO:0000255; WD40 protein Ciao1; Wdr39
Gene Symbols CIAO1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human CIAO1 (NP_0047951).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26371, 29231, 9391
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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