Invitrogen™ WDR39 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596650

Catalog No. PIPA596650

Description

Immunogen sequence: MKDSLVLLGR VPAHPDSRCW FLAWNPAGTL LASCGGDRRI RIWGTEGDSW ICKSVLSEGH QRTVRKVAWS PCGNYLASAS FDATTCIWKK NQDDFECVTT LEGHENEVKS VAWAPSGNLL ATCSRDKSVW VWEVDEEDEY ECVSVLNSHT QDVKHVVWHP SQELLASASY DDTVKLYREE EDDWVCCATL EGHESTVWSL AFDPSGQRLA SCSDDRTVRI WRQYLPGNEQ GVACSGSDPS WKCICTLSGF HSRTIYDIAW CQLTGALATA CGDDAIRVFQ EDPNSDPQQP TFSLTAHLHQ AHSQDVNCVA WNPKEPGLLA SCSDDGEVAF WKYQRPEGL; Positive Samples: Jurkat, Mouse kidney, Mouse thymus, Mouse heart, Rat heart.

WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.

Specifications

• Antigen: WDR39
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CIAO1
• Gene Alias: AW210570; CIA1; ciao1; ciao1 {ECO:0000255; cytosolic iron-sulfur assembly component 1; cytosolic iron-sulfur protein assembly 1; cytosolic iron-sulfur protein assembly 1 homolog; HAMAP-Rule:MF_03037}; probable cytosolic iron-sulfur protein assembly protein CIAO1; probable cytosolic iron-sulfur protein assembly protein CIAO1 {ECO:0000255; WD repeat domain 39; WD repeat-containing protein 39; WD repeat-containing protein 39 {ECO:0000255; WD40 protein Ciao1; Wdr39
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26371, 29231, 9391
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.68 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O76071, Q5M7T1, Q99KN2
• Gene Symbols: CIAO1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human CIAO1 (NP_0047951).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG