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Invitrogen™ WDR4 Recombinant Rabbit Monoclonal Antibody (JE58-28)
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Catalog No. PIMA542517
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PIMA542517 100 μL
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Catalog No. PIMA542517 Supplier Invitrogen™ Supplier No. MA542517
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Rabbit Recombinant Monoclonal Antibody

Positive Control: K562 cell lysates, human liver carcinoma tissue, human cervical carcinoma tissue, human ovarian tumor tissue, Daudi. Subcellular Location: Nucleus, Chromosome.

Required for 7-methylguanosine modification of tRNA. This protein is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes. including cell cycle progression. signal transduction. apoptosis. and gene regulation. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10). but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants. two of which diverge at the 3' UTR and thus encode the same protein products.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WDR4
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JE58-28
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene WDR4
Gene Accession No. P57081
Gene Alias AI415180; AI448349; D530049K22Rik; hWH; mWH; Protein Wuho homolog; TRM82; TRM82 tRNA methyltransferase 82 homolog; TRMT82; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat domain 4; WD repeat-containing protein 4; WD40 repeat protein 4; WDR4
Gene Symbols WDR4
Host Species Rabbit
Immunogen Recombinant protein within human WDR4 aa 262-412.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10785
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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