Invitrogen™ WDR5 Chimeric Recombinant Rabbit Monoclonal Antibody (RAB-C223)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA548332

Catalog No. PIMA548332

Description

Specificity: This antibody recognizes WDR5 (WD repeat-containing protein 5). It binds to a folded domain, amino acids 1-334. WDR5 is a protein that is involved in histone modification.

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.

Specifications

• Antigen: WDR5 Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P61964
• Gene Symbols: WDR5
• Immunogen: This antibody was obtained by recombinant antibody (rAb) phage display recognizing WDR5 protein under non-denaturing conditions.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG κ

• Applications: ChIP Assay, ELISA, Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: RAB-C223
• Conjugate: Unconjugated
• Gene: WDR5
• Gene Alias: 2410008O07Rik; AA408785; AA960360; Big; BIG3; BIG-3; BMP2-induced 3-kb gene protein; CFAP89; cilia and flagella associated protein 89; SWD3; SWD3, Set1c WD40 repeat protein, homolog; Unknown (protein for MGC:137327); WD repeat domain 5; WD repeat-containing protein 5; WD repeat-containing protein BIG-3; Wdr5; wu:fk47f04; zgc:56591; zgc:76895; zgc:76895 protein
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11091
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid