Invitrogen™ WDR5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102553

Catalog No. PIPA5102553

Description

Antibody detects endogenous levels of total WDR5.

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.

Specifications

• Antigen: WDR5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WDR5
• Gene Alias: 2410008O07Rik; AA408785; AA960360; Big; BIG3; BIG-3; BMP2-induced 3-kb gene protein; CFAP89; cilia and flagella associated protein 89; SWD3; SWD3, Set1c WD40 repeat protein, homolog; Unknown (protein for MGC:137327); WD repeat domain 5; WD repeat-containing protein 5; WD repeat-containing protein BIG-3; Wdr5; wu:fk47f04; zgc:56591; zgc:76895; zgc:76895 protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11091, 140858, 362093
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P61964, P61965, Q498M4
• Gene Symbols: WDR5
• Immunogen: A synthesized peptide derived from human WDR5(Accession P61964), corresponding to amino acid residues M1-S49.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov