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Invitrogen™ WDR59 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA559420
Description
Immunogen sequence: TSSQDNSVKF WDYRQPRKYL NILPCQVPVW KARYTPFSNG LVTVMVPQLR RENSLLLWNV FDLNTPVHTF VGHDDVVLEF QWRKQKEGSK D Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 99%.
As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210). [UniProt].
Specifications
WDR59 | |
Polyclonal | |
Unconjugated | |
WDR59 | |
FP977; GATOR complex protein WDR59; KIAA1923; WD repeat domain 59; WD repeat-containing protein 59; WDR59 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
79726 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q6PJI9 | |
WDR59 | |
Recombinant protein corresponding to Human WDR59. Recombinant protein control fragment (Product #RP-98626). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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