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Invitrogen™ WDR59 Polyclonal Antibody
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Catalog No. PIPA565506
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100 μL
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PIPA565506 100 μL
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Catalog No. PIPA565506 Supplier Invitrogen™ Supplier No. PA565506
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GSLTYSDPRER ERDQHDKNKR LLDPANTQQF DDFKKCYGEI LYRWGLREKR AEVLKFVSCP PDPHKGIEFG VYCSHCRSEV RGTQCAICKG FTFQCAIC Highest antigen sequence identity to the following orthologs - mouse 100%, rat 71%.

As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen WDR59
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene WDR59
Gene Accession No. Q6PJI9
Gene Alias FP977; GATOR complex protein WDR59; KIAA1923; WD repeat domain 59; WD repeat-containing protein 59; WDR59
Gene Symbols WDR59
Host Species Rabbit
Immunogen Recombinant Human WDR59. Recombinant protein control fragment (Product #RP-104851).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79726
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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