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Invitrogen™ WDR59 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565506

Catalog No. PIPA565506


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Description

Description

Immunogen sequence: GSLTYSDPRER ERDQHDKNKR LLDPANTQQF DDFKKCYGEI LYRWGLREKR AEVLKFVSCP PDPHKGIEFG VYCSHCRSEV RGTQCAICKG FTFQCAIC Highest antigen sequence identity to the following orthologs - mouse 100%, rat 71%.

As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210). [UniProt].
TRUSTED_SUSTAINABILITY
Specifications

Specifications

WDR59
Polyclonal
Unconjugated
WDR59
FP977; GATOR complex protein WDR59; KIAA1923; WD repeat domain 59; WD repeat-containing protein 59; WDR59
Rabbit
Antigen affinity chromatography
RUO
79726
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.05 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q6PJI9
WDR59
Recombinant Human WDR59. Recombinant protein control fragment (Product #RP-104851).
100 μL
Primary
Human
Antibody
IgG
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