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Invitrogen™ WDR65 Polyclonal Antibody
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Catalog No. PIPA555922
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100 μL
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Catalog No. Quantity
PIPA555922 100 μL
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Catalog No. PIPA555922 Supplier Invitrogen™ Supplier No. PA555922
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LKLTKKVRPQ EVSETEPSRD MLSTAPTARL NEQEETGRII EMQRLEIQRL RDQIQEQEQV TGFHTLAGVR LPSLSNSEVD LEVKTN Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 28%.

The WDR65 gene, which stands for WD Repeat Domain 65, encodes a protein characterized by the presence of WD repeat domains that facilitate protein-protein interactions. This gene is implicated in the assembly of a subset of inner arm dyneins, critical for ciliary motility and axonemal structure. Mutations in WDR65 have been associated with diseases such as Van der Woude syndrome (VWS) and related craniofacial disorders, highlighting its role in developmental processes. Specifically, a missense mutation in WDR65 was identified as a potential cause of VWS, suggesting that WDR65 is a target for regulatory factors like IRF6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WDR65
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CFAP57
Gene Accession No. Q96MR6
Gene Alias CFAP57; cilia and flagella associated protein 57; cilia- and flagella-associated protein 57; VWS2; WD repeat-containing protein 65; WDR65
Gene Symbols CFAP57
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human WDR65. Recombinant protein control fragment (Product #RP-94575).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 149465
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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