Invitrogen™ WDR65 Polyclonal Antibody

Catalog No.	Quantity
PIPA531657	100 μL

Catalog No. PIPA531657 Supplier Invitrogen™ Supplier No. PA531657

Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat. Predicted reactivity: Mouse (83%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The WDR65 gene, which stands for WD Repeat Domain 65, encodes a protein characterized by the presence of WD repeat domains that facilitate protein-protein interactions. This gene is implicated in the assembly of a subset of inner arm dyneins, critical for ciliary motility and axonemal structure. Mutations in WDR65 have been associated with diseases such as Van der Woude syndrome (VWS) and related craniofacial disorders, highlighting its role in developmental processes. Specifically, a missense mutation in WDR65 was identified as a potential cause of VWS, suggesting that WDR65 is a target for regulatory factors like IRF6.

Specifications

• Antigen: WDR65
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene: CFAP57
• Gene Accession No.: Q96MR6
• Gene Alias: CFAP57; cilia and flagella associated protein 57; cilia- and flagella-associated protein 57; VWS2; WD repeat-containing protein 65; WDR65
• Gene Symbols: CFAP57
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human WDR65. The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 149465
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG