Invitrogen™ WDR74 Monoclonal Antibody (OTI4B2)

Catalog No.	Quantity
PIMA526448	100 μL

Catalog No. PIMA526448 Supplier Invitrogen™ Supplier No. MA526448

Description

Mouse Monoclonal Antibody

WDR74 Monoclonal Antibody for Western Blot, IHC (P)

The yeast nucleolar protein NOP7 is necessary for the maturation of 66S preribosomes and interacts with numerous other proteins. One such protein is an essential, conserved WD repeat protein, NOP seven-associated protein 1 (NSA1), that is also required for the yeast 66S ribosome assembly. NSA1 is also associated with the AAA ATPase Rix7, and release of NSA1 from a novel late nucleolar pre-60S requires the Rix7 function. NSA1 has also been found upregulated in mammalian cancer cells, suggesting it may also play a role in cell proliferation.

Specifications

• Antigen: WDR74
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI4B2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: WDR74
• Gene Accession No.: Q6RFH5, Q8VCG3
• Gene Alias: 5730436H21Rik; AA407588; NOP seven-associated protein 1; NSA1; WD repeat domain 74; WD repeat-containing protein 74; Wdr74
• Gene Symbols: WDR74
• Host Species: Mouse
• Immunogen: Human recombinant protein fragment corresponding to amino acids 114-385 of WDR74 produced in E.coli.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 107071, 483778, 54663, 690229
• Target Species: Human, Mouse, Rat, Canine, Monkey
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1