Invitrogen™ WDR74 Monoclonal Antibody (OTI4F2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526443

Catalog No. PIMA526443

Description

WDR74 Monoclonal Antibody for Western Blot

The yeast nucleolar protein NOP7 is necessary for the maturation of 66S preribosomes and interacts with numerous other proteins. One such protein is an essential, conserved WD repeat protein, NOP seven-associated protein 1 (NSA1), that is also required for the yeast 66S ribosome assembly. NSA1 is also associated with the AAA ATPase Rix7, and release of NSA1 from a novel late nucleolar pre-60S requires the Rix7 function. NSA1 has also been found upregulated in mammalian cancer cells, suggesting it may also play a role in cell proliferation.

Specifications

• Antigen: WDR74
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6RFH5, Q8VCG3
• Gene Symbols: WDR74
• Immunogen: Human recombinant protein fragment corresponding to amino acids 114-385 of WDR74 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Monkey
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI4F2
• Conjugate: Unconjugated
• Gene: WDR74
• Gene Alias: 5730436H21Rik; AA407588; NOP seven-associated protein 1; NSA1; WD repeat domain 74; WD repeat-containing protein 74; Wdr74
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 107071, 483778, 54663, 690229
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid