Invitrogen™ West Nile Virus Envelope Monoclonal Antibody (GT3029)

Catalog No.	Quantity
PIMA535917	100 μL

Catalog No. PIMA535917

Supplier: Invitrogen™ MA535917

Description

Mouse Monoclonal Antibody

West Nile Virus Envelope Monoclonal Antibody for Western Blot, ICC/IF

West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.

Specifications

• Antigen: West Nile Virus Envelope
• Applications: Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: GT3029
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene Alias: West Nile envelope; West Nile Virus; WNV envelope
• Host Species: Mouse
• Immunogen: Recombinant protein encompassing a sequence within the center region of West Nile virus Envelope protein (West Nile virus (strain NY99-IC)). The exact sequence is proprietary.
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1