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Tocris Bioscience™ WH-4-023
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Catalog No. 541310
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54-131-0 10 mg
54-135-0 50 mg
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Catalog No. 54-131-0 Supplier Tocris Bioscience™ Supplier No. 5413/10
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Potent and selective Lck and Src inhibitor; also inhibits SIK

WH-4-023 is a potent and selective Lck and Src inhibitor (IC50 values are 2 and 6 nM respectively). Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases. Supports self-renewal of naive hESCs in combination with PD 0325901, CHIR 99021 and SB 590885 .

Specifications

Quantity 10 mg
Product Type WH-4-023
Purity >98%
Molecular Weight (g/mol) 568.67
Inhibitors WH-4-023

For Research Use Only

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