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Invitrogen™ WHSC2 Polyclonal Antibody
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Catalog No. PIPA558952
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100 μL
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PIPA558952 100 μL
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Catalog No. PIPA558952 Supplier Invitrogen™ Supplier No. PA558952
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LSLTREQMFA AQEMFKTANK VTRPEKALIL GFMAGSRENP CQEQGDVIQI KLSEHTEDLP KADGQGSTTM LVDTVFEMNY ATGQWTRFKK YKPMT Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WHSC2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NELFA
Gene Accession No. Q9H3P2
Gene Alias FLJ10442; FLJ25112; LOW QUALITY PROTEIN: negative elongation factor A; mWHSC2; Negative elongation factor A; negative elongation factor complex member A; negative elongation factor complex member A, Whsc2; Nelfa; NELF-A; P/OKcl.15; Whsc2; Whsc2h; Wolf-Hirschhorn syndrome candidate 2; Wolf-Hirschhorn syndrome candidate 2 homolog; Wolf-Hirschhorn syndrome candidate 2 protein
Gene Symbols NELFA
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human WHSC2. Recombinant protein control fragment (Product #RP-102878).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7469
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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