WIBG Mouse anti-Human, Clone: OTI11C5, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF806390
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOKey regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA; the relevance of RNA-binding remains unclear in vivo.
|Full length human recombit protein of human WIBG produced in HEK293T cell.|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 8% trehalose and no preservative; pH 7.3|
|-20° C, Avoid Freeze/Thaw Cycles|
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