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Description
WIC1 is an inhibitor of the canonical Wnt/β-catenin signaling pathway. In vitro, it reduces ABSC (Airway Basal Stem Cell) proliferation and induces ciliated epithelial cell differentiation, in a model of squamous lung cancer. WIC1 also represses the phosphorylation of β-cateninY489 and Tp63 expression.
Greener Choice Claims
- Environmental benefits include:
- Ozone-Safe or Safe for the Ozone Layer
Specifications
Specifications
Chemical Name or Material | N-[4-(4-Ethyl-1-piperazinyl)phenyl]-2-oxo-2 H-1-benzopyran-3-carboxamide |
CAS | 943083-58-7 |
Quantity | 10 mg |
Target | beta-Catenin |
Molecular Formula | C22H23N3O3 |
Purity | 0.98 |
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Product Title
Tocris Bioscience⢠WIC1 >
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