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Tocris Bioscience™ WIC1
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Catalog No. 758050
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50 mg
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Catalog No. Quantity
75-805-0 50 mg
75-801-0 10 mg
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Catalog No. 75-805-0 Supplier Tocris Bioscience™ Supplier No. 7580/50
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Description

Inhibitor of Wnt/β-catenin signaling

WIC1 is an inhibitor of the canonical Wnt/β-catenin signaling pathway. In vitro, it reduces ABSC (Airway Basal Stem Cell) proliferation and induces ciliated epithelial cell differentiation, in a model of squamous lung cancer. WIC1 also represses the phosphorylation of β-cateninY489 and Tp63 expression.

Specifications

Chemical Name or Material N-[4-(4-Ethyl-1-piperazinyl)phenyl]-2-oxo-2 H-1-benzopyran-3-carboxamide
CAS 943083-58-7
Quantity 50 mg
Target beta-Catenin
Molecular Formula C22H23N3O3
Purity 0.98
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