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Tocris Bioscience™ WIKI4
GREENER_CHOICE

Catalog No. 485525
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Potent tankyrase inhibitor

WIKI4 is an inhibitor of Wnt/β-catenin signaling (EC50 ∼ 75 nM). Inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ∼15 nM); prevents the ubiquitination and degradation of axin. WIKI4 inhibits expression of β-catenin target genes in cancer cell lines as well as in human embryonic stem cells (ESC).

WIKI4 synthesized to Ancillary Material Grade also available.

Specifications

Chemical Name or Material 2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
CAS 838818-26-1
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C29H23N5O3S
Formula Weight Observed MW: 521.59
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