WIPI1 Mouse anti-Human, Clone: OTI11B11, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811510

Catalog No. 50-167-0699

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.

Specifications

• Antigen: WIPI1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: WIPI1
• Gene Alias: ATG18, ATG18A, WIPI49
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55062
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI11B11
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q5MNZ9
• Gene Symbols: WIPI1
• Immunogen: Human recombit protein fragment corresponding to amino acids 195-446 of human WIPI1 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1