Invitrogen™ WIPI1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534973

Catalog No. PIPA534973

Description

Recommended positive controls: human WIPI1-transfected 293T cells, mouse muscle. Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.

Specifications

• Antigen: WIPI1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WIPI1
• Gene Alias: 4930533H01Rik; ATG18; Atg18 protein homolog; ATG18A; AW411817; D11Ertd498e; RGD1307754; WD repeat domain phosphoinositide-interacting protein 1; WD repeat domain, phosphoinositide interacting 1; WD40 repeat protein interacting with phosphoinositides of 49 kDa; WD40 repeat protein Interacting with phosphoInositides of 49kDa; WIPI 49 kDa; Wipi1; WIPI-1; WIPI-1 alpha; WIPI49
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 52639, 55062
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q5MNZ9, Q8R3E3
• Gene Symbols: WIPI1
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human WIPI1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG