WIPI1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5110581

Catalog No. PIPA5110581

Description

Immunogen sequence: GTLAAITFNA SGSKLASASE KGTVIRVFSV PDGQKLYEFR RGMKRYVTIS SLVFSMDSQF LCASSNTETV HIFKLEQVTN SRPEEPSTWS GYMGKMFMAA TNYLPTQVSD MMHQDRAFAT ARLNFSGQRN ICTLSTIQKL PRLLVASSSG HLYMYNLDPQ DGGECVLIKT HSLLGSGTTE ENKENDLRPS LPQSYAATVA RPSASSASTV PGYSEDGGAL RGEVIPEHEF ATGPVCLDDE NEFPPIILCR GNQKGKTKQS

WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.

Specifications

• Antigen: WIPI1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WIPI1
• Gene Alias: 4930533H01Rik; ATG18; Atg18 protein homolog; ATG18A; AW411817; D11Ertd498e; RGD1307754; WD repeat domain phosphoinositide-interacting protein 1; WD repeat domain, phosphoinositide interacting 1; WD40 repeat protein interacting with phosphoinositides of 49 kDa; WD40 repeat protein Interacting with phosphoInositides of 49kDa; WIPI 49 kDa; Wipi1; WIPI-1; WIPI-1 alpha; WIPI49
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 303630, 52639, 55062
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.46 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q5MNZ9, Q8R3E3
• Gene Symbols: WIPI1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 187-446 of human WIPI1 (NP_060453.3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov