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Invitrogen™ WISP3 Polyclonal Antibody
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Catalog No. PIPA585059
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100 μL
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PIPA585059 100 μL
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Catalog No. PIPA585059 Supplier Invitrogen™ Supplier No. PA585059
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GTGPLDTTPE GRPGEVSDAP QRKQFCHWPC KCPQQKPRCP PGV Highest antigen sequence indentity to the following orthologs: Rat - 56%, Mouse - 56%.

WISP3 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of the WISP3 gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WISP3
Applications Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CCN6
Gene Accession No. O95389
Gene Alias CCN family member 6; CCN6; Cellular communication network factor 6; ENSMUSG00000062074; Gm735; LIBC; PPAC; PPD; RGD1564120; UNQ462/PRO790/PRO956; Wisp3; WISP-3; WNT1 inducible signaling pathway protein 3; WNT1-inducible-signaling pathway protein 3
Gene Symbols CCN6
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human WISP3. Recombinant protein control fragment (Product #RP-107316).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8838
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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