Tocris Bioscience Withaferin A
Inhibits NF-κB activation
Manufacturer: Tocris Bioscience 2816/1
DescriptionSteroid lactone that displays anti-inflammatory, antitumor and antiangiogenic activity. Inhibits endothelial cells (HUVEC) sprouting in vitro (IC 50 = 12 nM) and in vivo. Prevents NF-κB activation by inhibiting activation of IKKβ. Also inhibits chymotrypsin-like activity of the 20S proteasome.
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