Invitrogen™ WIZ Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA519066

Catalog No. PIPA519066

Description

This antibody is predicted to react with mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.

WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its message was found to be expressed in the granule cell layers of the cerebellum as well as in the dentate gyrus and olfactory bulb. Later analysis indicates however that WIZ is ubiquitously expressed. WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. WIZ can also associate with CtBP family proteins, known to be transcriptional co-repressors, and has been suggested to link G9a/GLP complexes to the CtBP co-repressor machinery, possibly regulating complex stability and gene silencing.

Specifications

• Antigen: WIZ
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WIZ
• Gene Alias: Protein Wiz; widely interspaced zinc finger motifs; widely-interspaced zinc finger motifs; widely-interspaced zinc finger-containing protein; Wiz; WIZ zinc finger; zinc finger protein 803; ZNF803
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 58525
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O95785
• Gene Symbols: WIZ
• Immunogen: Synthetic peptide sequence (RSYIQGGRPFTKKFR) corresponding to the internal amino acids of WIZ (aa 1453-1468).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG