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Tocris™ WM 8014
GREENER_CHOICE

Catalog No. 669310
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Potent and selective KAT6A and KAT6B inhibitor

WM 8014 is a potent and selective lysine acetyltransferase KAT6A and KAT6B inhibitor (IC50 values are 8 and 28 nM, respectively). Exhibits > 10-fold selectivity for KAT6A/B over KAT7 and KAT5, and no significant activity against KAT8, KAT2A/2B, and KAT3A/B. Induces cell cycle arrest in G1/G0 in MEFs and inhibits proliferation of lymphoma cells in vitro. Cell permeant. Suitable for use in vitro.

Specifications

Chemical Name or Material N'-(4-Fluoro-5-methyl-[1,1 '-biphenyl]-3-carbonyl)benzenesulfonohydrazide
CAS 2055397-18-5
Quantity 10 mg
Target Histone Acetyltransferase Inhibitors
Molecular Formula C20H17FN2O3S
Purity 0.98
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