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  4. Invitrogen™ Human WNK1, His Tag Recombinant Protein 

Invitrogen™ Human WNK1, His Tag Recombinant Protein

Catalog No. A33513
Encompass_Preferred
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Quantity:
1 mg
10 μg
100 μg

Description

Recombinant Protein

WNK1 serine/threonine kinase is a member of the WNK subfamily. WNK1 may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. WNK plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9H4A3
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM HEPES with 100 mM NaCl, 20% glycerol, 5 mM DTT and no preservative; pH 7.5
Gene ID (Entrez) 65125
Molecular Weight (g/mol) 47 kDa
Name Human WNK1, His Tag
Quantity 10 μg
Gene Alias 6430573H23Rik; EG406236; Erythrocyte 65 kDa protein; HSAN2; HSN2; hWNK1; KDP; KIAA0344; Kinase deficient protein; MGC163339; MGC163341; mKIAA0344; p65; PPP1R167; Prkwnk1; prostate-derived sterile 20-like kinase; protein kinase lysine-deficient 1; Protein kinase with no lysine 1; protein phosphatase 1, regulatory subunit 167; PSK; Serine/threonine-protein kinase WNK1; serine/threonine-protein kinase WNK1 1; serine/threonine-protein kinase WNK1 2; With no K; WNK lysine deficient protein kinase 1; WNK lysine deficient protein kinase 1 isoform; WNK1
Common Name WNK1
KinaseFamily WNK Kinase Family
Protein Length 171-529
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-tag
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Shipping Condition Dry Ice
Expression System Insect cells
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Active, Catalytic
Form Liquid
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