Invitrogen™ WNT10A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102852

Catalog No. PIPA5102852

Description

Antibody detects endogenous levels of total Wnt10a.

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.

Specifications

• Antigen: WNT10A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WNT10A
• Gene Alias: OODD; Protein Wnt-10a; SSPS; STHAG4; wingless related MMTV integration site 10a; wingless-type MMTV integration site family member 10A; wingless-type MMTV integration site family, member 10A; Wnt family member 10A; Wnt10a
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 316527, 80326
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9GZT5
• Gene Symbols: WNT10A
• Immunogen: A synthesized peptide derived from human WNT10A(Accession Q9GZT5), corresponding to amino acid residues C61-E111.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov