WNT3 Monoclonal Antibody (OTI3F5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA801737

Catalog No. 50-167-8954

Description

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

Specifications

• Antigen: WNT3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P56703
• Gene Symbols: WNT3
• Immunogen: Human recombit protein fragment corresponding to amino acids 128-355 of human WNT3 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI3F5
• Conjugate: Unconjugated
• Gene: WNT3
• Gene Alias: INT4, TETAMS
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7473
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid